Table 3.
Outcome Feature Sets | Fail Safe n | Z Kendall’s τ | p | Egger’s t Test (df) | p | Missing Studies (Side) | After Adjusting | |
---|---|---|---|---|---|---|---|---|
SMD | 95%CI | |||||||
TRP | −10.30 | 1.819 | 0.034 | 3.063 (27) | 0.002 | 5 (Right) | −0.324 | −0.548; −0.101 |
TRP/CAAs | −4.785 | 0.300 | 0.381 | 1.142 (5) | 0.152 | 2 (Left) | −0.748 | −1.069; -0.427 |
KYN/TRP (Psychotic) | 1.827 | 0.339 | 0.367 | 0.764 (2) | 0.262 | - | - | - |
KA/KYN (Suicidal) | −3.342 | 0.600 | 0.274 | 0.663 (5) | 0.268 | 2 (Left) | −0.337 | −0.541; −0.133 |
(KYN + 3HK + 3HA + XA + QA + PA) | −0.094 | 0.705 | 0.240 | 0.892 (24) | 0.190 | 3 (Right) | 0.210 | −0.046; 0.467 |
KA | −5.072 | 0.549 | 0.291 | 0.692 (11) | 0.251 | - | - | - |
AA | −2.199 | 0.000 | 0.500 | 0.422 (1) | 0.372 | 1 (Right) | −0.215 | −0.430; 0.00006 |
QA | 3.846 | 0.985 | 0.162 | 1.618 (12) | 0.065 | 3 (Right) | 0.646 | 0.228; 1.065 |
TRP: tryptophan. KYN: kynurenine. KA: kynurenic acid. 3HK: 3-Hydroxykynurenine. 3HA: 3-Hydroxyanthranilic acid. XA: xanthurenic acid. QA: quinolinic acid. PA: picolinic acid. AA: anthranilic acid. CAAs: competing amino acids (valine + phenylalanine + tyrosine + leucine + isoleucine).