Effects of daily consumption of monosodium glutamate (MSG) for 8 weeks at the dose of 80, 160, and 320 mg/kg BW/day on renal vascular resistance (RVR, A), renal blood flow (RBF, B), glomerular filtration rate (GFR, C), osmolar clearance (Cosm, D), negative free water clearance (TCH2O, E), urine flow rate (, F), urine osmolarity (Uosm, G), plasma osmolarity (Posm, H), and hematocrit (I) in the sham operative (SO) and the 2-kidneys-1-clip (2K1C) groups. Data expressed as mean ± S.E.M. ∗p < 0.05 in comparison between groups.