The expression of METTL3 at different stages of atherosclerosis, analyzed by immunohistochemical assay: (A) The expression level of METTL3 at Stage 0 of atherosclerosis. (B) The expression level of METTL3 at Stage 1 of atherosclerosis. (C) The expression level of METTL3 at Stage 2 of atherosclerosis. (D) The expression level of METTL3 at Stage 3 of atherosclerosis. (E) The expression level of METTL3 at Stage 4 of atherosclerosis. (F) The bar chart and differences between the other groups and Stage 1. Stage 0, normal tunica intima; Stage 1, fatty streak tunica intima; Stage 2, fibrous plaques tunica intima; Stage 3, atherosclerotic tunica intima; Stage 4, secondary affection tunica intima. Low magnification (40×); scale bar: 200 μm. High magnification (200×); scale bar: 50 μm. * p < 0.05. *** p < 0.001.