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. 2022 Oct 10;11(19):3180. doi: 10.3390/cells11193180

Figure 2.

Figure 2

Prevalence of FGFR alterations in selected tumor types. For each tumor type, the prevalence of amplifications, mutations, fusions or translocations and overexpression is highlighted according to [34,35,36,37,38,39,40,42,43,44,45,46,47,48,49,50,51,113,114,115,116,117,118,119,120,121,122,123,124,125,126]. Overexpression relates to protein overexpression as (usually) detected via immunohistochemistry. FGFR1 data marked with * for cholangiocarcinoma represent mRNA expression data. The most prevalent alteration is depicted in bold for each tumor type. FGFR: fibroblast growth factor receptor; HNSCC: Head and Neck Squamous Cell Carcinoma; NSCLC: Non-Small-Cell Lung Cancer.