Table 1.
Summary of clinical parameters of Creutzfeldt–Jakob disease patients, an Alzheimer’s disease (AD) patient, and age- and gender-matched human post-mortem control brain samples displayed in this review. All cases underwent standardized neuropathological assessment, including macroscopic and microscopic examination. sCJD and AD diagnoses were neuropathologically confirmed according to current criteria. Controls did not show any sign of neurologic or neurodegenerative diseases [73,97].
| Patient | Disease | Age | Gender | ABC Score | CJD Subtype | Cause of Death |
|---|---|---|---|---|---|---|
| 1 | sporadic CJD | 78 | M | — | MV2K+C | CJD |
| 2 | sporadic CJD | 69 | F | — | VV1 | CJD |
| 3 | sporadic CJD | 77 | F | — | MM/MV1 | CJD |
| 4 | Control | 69 | F | — | — | Bronchogenic adenocarcinoma |
| 5 | Control | 79 | M | — | — | Ventricular fibrillation |
| 6 | AD | 80 | M | A3B2C3 | — | Dementia |