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. Author manuscript; available in PMC: 2022 Nov 19.
Published in final edited form as: N Engl J Med. 2022 Apr 4;386(20):1877–1888. doi: 10.1056/NEJMoa2109191

Figure 2. (facing page). Cumulative Risk of Cardiovascular Events According to Categories of the Combined-Risk z Score and Age.

Figure 2

The cumulative risk of cardiovascular events is shown as the estimated probability according to the combined-risk z score and age (Kaplan–Meier method). The horizontal dashed line in each panel indicates the overall risk of the event. Panel A shows the hazard ratios for fatal cardiovascular events, and Panel B the hazard ratios for fatal or nonfatal cardiovascular events. All participants were included in these analyses; there were 319 fatal events and a mean of 1563 fatal or nonfatal events across imputations. In each panel, the inset shows the same data on an enlarged y axis. The columns of tabular data below the graphs correspond to the following ages (in years): 25.0, 27.5, 32.5, 37.5, 42.5, 47.5, 52.5, 57.5, and 62.5.