Figure 7.
MIR4435-2HG was highly expressed in HNSCC tissues and promoted cell migration and invasion. (A) The expression of 5 m6A-related eRNAs between 43 tumor tissues and paired normal tissues in the TCGA-HNSCC cohort; (B) the expression of 5 m6A-related eRNAs between 20 HNSCC tissues and paired ANNT; (C) RT-qPCR analysis of SCC25 and CAL27 cells after transfection with si-MIR4435-2HG; (D) wound-healing assay images of SCC25 and CAL27 cells after transfection with si-MIR4435-2HG; Magnification at 40×; (E,F) representative photographs (E) and plots of statistical analysis (F) of migration and invasion assays of SCC25 and CAL27 cells after transfection with si-MIR4435-2HG; Magnification at 100×. The experiment was repeated three times; error bars indicate SD. (** p < 0.01, *** p < 0.001).