Table 2.
Burn research has led to the development of novel treatment strategies in burn care. The prevention of burn wound progression with novel therapeutics, alternative methods to conventional split-thickness skin grafting (STSG) to provide wound coverage, as well as advancements in infection control, fluid resuscitation, pain management and nutritional support, has increased the survival rate and enhanced healing outcomes following severe burn injury.
| Major Burn (>20% TBSA) | |
|---|---|
| Local Treatment | Systemic Treatment |
| Prevention of burn conversion | Burn shock |
| Topical treatment | Fluid resuscitation |
| Systemic pharmacological agents | |
| Infection control | Hypermetabolic state |
| Topical antimicrobials | Nutrition support |
| Systemic antibiotics | |
| Removal of necrotic tissue | Sepsis |
| Surgical debridement | Systemic antibiotics |
| Enzymatic debridement | |
| Barrier function restoration | Pain control |
| STSG | Opiates |
| Minced skin transplantation | NSAID |
| Cell therapy | |