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. Author manuscript; available in PMC: 2023 Sep 29.
Published in final edited form as: Cell. 2022 Sep 29;185(20):3807–3822.e12. doi: 10.1016/j.cell.2022.09.015

Figure 6. Candida species are present in GI cancers and high abundance is associated with early-stage stomach cancer.

Figure 6.

(A – B) Targeted analysis measuring abundance (RPKM) of C. albicans and C. tropicalis (A) and S. cerevisiae (B) across TCGA cancer types.*

(C – D)Abundance of C. albicans, C. tropicalis (C), and S. cerevisiae (D) are elevated in stage 1 stomach cancer tumors and stage 4 colon cancer tumors. Significance was calculated between stage 1 tumors and each subsequent stage.*

* The direction of the inequality symbol indicates which sample group is greater, while the number of symbols indicates the degree of statistical significance, determined by a two-sided Wilcoxon rank-sum statistic (1: p < 0.05, 2: p < 0.01, 3: p < 0.001).