Table 3.

Multivariable analysis for those factors associated with overall survival.

Parameter	HR	95%CI	p-Value
Performance status (ref = 0–1)	2.78	[1.77–4.38]	<0.0001
PPI intake (ref = no)	2.00	[1.34–2.99]	0.0008
Tumor location (ref: RCC)	2.51	[1.62–3.89]	<0.0001
Hemoglobin (g/dL)	0.90	[0.82−0.99]	0.0303
PMN/lymphocyte ratio	1.13	[1.08–1.19]	<0.0001

HR: hazard ratio; CI: confidence interval; PPIs: proton pump inhibitors; RCC: renal cell cancer; PMN: polymorphonuclear neutrophils.