Figure 1.

Response of sensitive versus resistant TCCSUP, T24, RT112, and RT4 bladder cancer cell lines to gemcitabine (upper graphs) and cisplatin (lower graphs). Cell lines were exposed to the compounds, the cell number was evaluated after 24, 48, and 72 h using the MTT assay, and the 24–72 h increase was determined. Differences between the cell number increase of drug-treated and non-treated (control) cells are presented as percentage drug efficacy, indicating a percentage cell number reduction. Negative values indicate an increase in the cell number under drug treatment, compared to the control. The 24–72 h cell growth data are shown in the Supplementary Materials (Figure S1). Error bars indicate the standard deviation. * indicates a significant reduction in the tumor cell number, compared to the corresponding control, n = 6.