Table 1.

Multivariate analysis between clinical parameters (T-stage, ISUP grade, and PSA level) and GAG motifs (total HS, D2S0/D0S6, D2S6, D0a10 relative abundance, and 6S-CS/4S-CS ratio), FDR controlled p-values, and hazard ratios with 95% confidence intervals are presented. See Figure 1 for resolving the GAG structure codes.

	Total HS		D2S0/D0S6		D2S6		D0a10		6S-CS/4S-CS Ratio
Clinical Parameter	p-Value	HR	p-Value	HR	p-Value	HR	p-Value	HR	p-Value	HR
T-stage	0.0573	0.36 (0.13–1.00)	0.0252	3.97 (1.32–11.92)	0.0152	4.63 (1.59–13.54)	0.0525	3.30 (1.23–8.85)	0.1807	0.40 (0.13–1.27)
PSA level	0.1595	0.45 (0.15–1.37)	0.032	3.43 (1.20–9.82)	0.0252	3.90 (1.34–11.29)	0.1807	2.31 (0.84–6.37)	0.2294	0.50 (0.16–1.56)
ISUP grade	0.0456	0.33 (0.12–0.93)	0.0151	5.17 (1.73–15.51)	0.0026	8.72 (2.70–28.16)	0.0525	3.45 (1.31–9.04)	0.2063	0.45 (0.15–1.41)