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. 2022 Sep 30;14(19):4802. doi: 10.3390/cancers14194802

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Microglia infiltration is associated with the mRNA expression of immune checkpoint genes and immune regulatory pathways. (A). Spearman correlation coefficient (SCC) between PC1 and the mRNA expression of several immune checkpoint genes. (B). SCC between PC1 and mRNA genes expressed in microglia. (C). SCC between PC1 and CD86 and MSR1 mRNA levels. (D). SCC between PC1 and a macrophage regulation score. (E). SCC between PC1 and leukocyte and lymphocyte infiltration. (F). SCC between PC1 and IFNγ response and TGFβ response.