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TAM mutations exacerbate early lethality in APP/PS1 mice. Percent survival of mouse populations of the indicated genotypes and indicated sizes (n = number of mice monitored) as a function of age (postnatal day). Dotted vertical indicates the time at which Aβ plaques are reliably detected in the APP/PS1 line. Indicated P values calculated by log-rank test. In this and all subsequent figures, differences that are not statistically significant do not have a specified P value.
