TABLE 1.
The characteristics of the patients at the base line
| Parameters | Units / category | Experimental (N = 121) | Placebo (N = 121) | p |
|---|---|---|---|---|
| Age | years | 30.0 ± 3.1 | 30.4 ± 3.5 | 0.221 |
| Body mass index | kg/m2 | 27.4 ± 4.0 | 27.7 ± 3.6 | 0.535 |
| ≥18.5, <25.0 | 35 | 28 | 0.528 | |
| ≥25.0, <30.0 | 61 | 62 | ||
| ≥30.0 | 25 | 31 | ||
| Pregnancy | Count | 1.5 ± 1.1 | 1.4 ± 0.7 | 0.439 |
| 1 | 84 | 89 | ||
| 2 | 23 | 25 | ||
| 3 | 11 | 5 | ||
| 4 | 2 | 1 | ||
| 5 | 0 | 1 | ||
| 9 | 1 | 0 | ||
| Diabetes mellitus | Any | 17 | 19 | 0.718 |
| Gestational only | 16 | 18 | 0.711 | |
| Hypertension | Chronic | 0 | 2 | 0.262 |
| Gestational | 4 | 5 | ||
| Pre‐eclampsia | 0 | 3 | ||
| Gestational age | weeks | 39.5 ± 1.1 | 39.5 ± 1.1 | 0.853 |
| Hemoglobin pre‐CS | g/L | 119.6 ± 11.8 | 118.6 ± 11.7 | 0.490 |
| WBC count pre‐CS | ×109/L | 8.36 ± 1.8 | 8.9 ± 2.2 | 0.119 |
| 4.5–10 | 101 | 90 | 0.083 | |
| ≥10 | 20 | 31 | ||
| NEU% pre‐CS | % | 71.8 ± 6.6 | 73.1 ± 6.5 | 0.106 |
| <60 | 5 | 3 | 0.656 | |
| ≥60, <75 | 74 | 71 | ||
| ≥75 | 42 | 47 | ||
| hsCRP pre‐CS | mg/L | 13.5 ± 13.8 | 13.5 ± 17.4 | 0.990 |
| <10 | 70 | 73 | 0.571 | |
| ≥10 | 48 | 43 | ||
| Missing data | 3 | 5 | ||
| Procalcitonin pre‐CS | μg/L | 0.08 ± 0.07 | 0.06 ± 0.04 | 0.149 |
| <0.05 | 53 | 52 | 0.755 | |
| ≥0.05 | 61 | 65 | ||
| Missing data | 7 | 4 | ||
| Body temperature pre‐CS | °C | 36.9 ± 0.3 | 36.9 ± 0.3 | 0.671 |
| <37 | 55 | 52 | 0.651 | |
| ≥37.0, <37.5 | 62 | 66 | ||
| ROM duration | hours | 15.0 ± 17.9 | 14.5 ± 17.9 | 0.845 |
| No | 4 | 6 | 0.398 | |
| <24 | 96 | 87 | ||
| ≥24 | 21 | 28 | ||
| ROM type | No | 4 | 6 | 0.060 |
| Spontaneously before labor | 77 | 87 | ||
| Spontaneously in labor | 8 | 2 | ||
| Iatrogenic ROM induction | 32 | 26 | ||
| Cervix dilatation | cm | 3.4 ± 2.4 | 3.6 ± 2.4 | 0.632 |
| <6 | 97 | 98 | 0.807 | |
| ≥6, <10 | 23 | 21 | ||
| 10 | 1 | 2 | ||
| Labor duration | hours | 5.4 ± 4.9 | 5.8 ± 4.9 | 0.505 |
| 0 | 30 | 27 | 0.953 | |
| ≥0.5, <6.0 | 38 | 38 | ||
| ≥6.0, <12.0 | 42 | 43 | ||
| ≥12.0 | 11 | 13 | ||
| CS ondication | Failure to progress | 57 | 52 | 0.524 |
| Fetal distress | 39 | 43 | ||
| Failed induction | 7 | 12 | ||
| Others | 18 | 14 | ||
Note: Data are mean ± standard deviation, or n.
Abbreviations: CS, cesarean section; hsCRP, hypersensitive C‐reactive protein; NEU%, percentage of neutrophils; ROM, rupture of membrane; WBC, white blood cells.