Table 3. Participant baseline clinical characteristics for Stage II (n = 25).
| Type of Primary Cancer* | Number n (%) | Type of pain** (n) |
|---|---|---|
| Breast + bone metastasis | 5 (20%) | Neuropathic (2) |
| Neuropathic, Nociceptive (1) | ||
| Bone pain (2) | ||
| Breast + lung + bone metastasis | 1 (4%) | Neuropathic, Bone pain |
| Breast + liver + bone metastasis | 1 (4%) | Neuropathic, Bone pain |
| NSCLC + brain + bone metastasis | 4 (16%) | Neuropathic, Visceral, Neuropathic, Bone pain |
| NSCLC + bone metastasis | Neuropathic, Nociceptive, Somatic, Bone pain | |
| NSCLC + adrenal gland + liver metastasis | Neuropathic, Nociceptive, Somatic, Bone pain | |
| Lung + bone metastasis | Nociceptive, Visceral, Bone pain | |
| Gastrointestinal | 4 (16%) | |
| • Oropharyngeal + lung metastasis + lymph nodes | Neuropathic | |
| • Oesophageal + liver + lung metastasis | Nociceptive, Visceral, Neuropathic | |
| • Large bowel + peritoneum + lung + bone metastasis | Neuropathic, Nociceptive, Visceral | |
| • Appendix mucinous + peritoneum metastasis | Neuropathic | |
| Hematological | 3 (12%) | |
| • Diffuse large cell lymphoma | Neuropathic | |
| • CLL + SCC scalp metastasis | Neuropathic | |
| • Multiple Myeloma + BPH | Chronic Bone pain | |
| Pancreas + lung + liver + adrenal gland | 1 (4%) | Nociceptive, Visceral, Neuropathic |
| Pancreas + left adrenal + peritoneum + mediastinum + para-aortic and mesenteric lymph node metastasis | 1 (4%) | Neuropathic, Visceral |
| Ovaries + liver + lung metastasis | 1 (4%) | Nociceptive, Visceral, Bone pain |
| Ovaries + breast + groin + abdominal lymph nodes metastasis | 1 (4%) | Nociceptive, Visceral |
| Melanoma + bone metastasis | 1 (4%) | Neuropathic |
| Central Nervous System | 1 (4%) | Neuropathic |
| Prostate + bone metastasis | 1 (4%) | Neuropathic |
*All eligible enrolled patients were diagnosed with advanced incurable malignancy with intractable pain unrelieved by opioids.
**Some patients presented with more than one type of pain.
NSCLC = Non-Small Cell Lung Cancer; CLL = Chronic Lymphocytic Leukemia; SCC = Squamous Cell Carcinoma; BPH = Benign Prostatic Hypertrophy.