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. 2022 Sep 27;12(19):3372. doi: 10.3390/nano12193372

Table 5.

Results of cell viability assay of plain CHX solution and liposomal CHX.

Samples Test Conc. (μg/mL) Cell Viability (%) IC50 (μg/mL)
L929 Cells 3T3 Cells L929 Cells 3T3 Cells
Plain CHX solution 250 10.41 ± 0.30 16.93 ± 0.13 12.32 ± 3.65 29.07 ± 2.14
125 10.41 ± 0.11 18.94± 1.23
62.5 10.46 ± 0.23 36.22 ± 0.44
31.25 12.10 ± 0.39 43.04 ± 0.36
15.62 47.95 ± 0.49 61.47 ± 0.11
7.81 72.88 ± 0.30 76.31 ± 0.98
Liposomal CHX 250 10.05 ± 0.17 26.98 ±0.76 37.90 ± 1.05 85.24 ± 3.22
125 10.18 ± 0.39 43.32 ± 1.28
62.5 10.26 ± 0.09 64.05 ± 0.03
31.25 69.04 ± 0.56 69.53 ± 0.48
15.62 89.59 ± 0.22 75.99 ± 1.11
7.81 95.34 ± 1.65 82.67 ± 0.73

The results are presented as mean ± SD, n = 3. CHX: Chlorhexidine digluconate; IC50: Half-maximal inhibitory concentration.