Table 5.
Samples | Test Conc. (μg/mL) | Cell Viability (%) | IC50 (μg/mL) |
||
---|---|---|---|---|---|
L929 Cells | 3T3 Cells | L929 Cells | 3T3 Cells | ||
Plain CHX solution | 250 | 10.41 ± 0.30 | 16.93 ± 0.13 | 12.32 ± 3.65 | 29.07 ± 2.14 |
125 | 10.41 ± 0.11 | 18.94± 1.23 | |||
62.5 | 10.46 ± 0.23 | 36.22 ± 0.44 | |||
31.25 | 12.10 ± 0.39 | 43.04 ± 0.36 | |||
15.62 | 47.95 ± 0.49 | 61.47 ± 0.11 | |||
7.81 | 72.88 ± 0.30 | 76.31 ± 0.98 | |||
Liposomal CHX | 250 | 10.05 ± 0.17 | 26.98 ±0.76 | 37.90 ± 1.05 | 85.24 ± 3.22 |
125 | 10.18 ± 0.39 | 43.32 ± 1.28 | |||
62.5 | 10.26 ± 0.09 | 64.05 ± 0.03 | |||
31.25 | 69.04 ± 0.56 | 69.53 ± 0.48 | |||
15.62 | 89.59 ± 0.22 | 75.99 ± 1.11 | |||
7.81 | 95.34 ± 1.65 | 82.67 ± 0.73 |
The results are presented as mean ± SD, n = 3. CHX: Chlorhexidine digluconate; IC50: Half-maximal inhibitory concentration.