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. 2022 Oct 9;19(19):12911. doi: 10.3390/ijerph191912911

Table 4.

Variables associated with cognitive impairment.

Variable Totals
n (%)
213 (100)
Risk CI
n (%)
52 (24.4)
No Risk CI
n (%)
161 (75.6)
p-Value
1. Sociodemographic Factors
Age
(x¯ ± s) 72.8 ± 11.2 78.9 ± 7.7 71.0 ± 11.5 <0.001 a ***
[50, 65) 57 (27.1) 1 (2.0) 56 (35.0) <0.001 b ***
[65, 80) 85 (40.5) 25 (51.0) 60 (37.0)
[80, 95] 68 (32.4) 23 (47.0) 45 (28.0)
Marital status
Married 139 (65.6) 26 (51.0) 113 (70.2) 0.013 b *
Widow 57 (26.9) 22 (43.1) 35 (21.7)
Separated/Divorced 6 (2.8) 0 (0.0) 6 (3.7)
Single 10 (4.7) 3 (5.9) 7 (4.3)
2. Cognitive Impairment
Subjective memory complaint
Yes 79 (37.1) 25 (48.1)
27 (51.9)
54 (33.5)
107 (66.5)
0.070 c
No 134 (62.9)
Memory Impairment Screen (MIS) [0, 8]
(x¯ ± s) 6.8 ± 1.9 4.9 ± 2.7 7.4 ± 1.1 <0.001 d ***
CI risk [0, 4] 21 (9.9) 21 (40.4) 0 (0.0) <0.001 b ***
No CI risk (4, 8] 191 (90.1) 31 (59.6) 160 (100.0)
Short Portable Mental State Questionnaire (SPMSQ) [0, 10]
(x¯ ± s) 1.1 ± 1.3 2.4 ± 1.6 0.7 ± 0.9 <0.001 d ***
CI risk [3–4, 10)
No CI risk [0, 3–4)
28 (13.1) 28 (53.8) 0 (0.0) <0.001 b ***
185 (86.9) 24 (46.2) 161 (100.0)
Semantic Verbal Fluency (SVF) [0, +∞)
(x¯ ± s)
17.4 ± 7.1 13.5 ± 5.1 18.7 ± 7.2 <0.001 d ***
CI risk [0, 10]
No CI risk [10, +∞)
16 (7.5) 16 (30.8) 0 (0.0) <0.001 b ***
196 (92.5) 36 (69.2) 160 (100.0)
3. Meaning in Life
Purpose in life (PiL) [6, 36]
(x¯ ± s)
29.6 ± 5.6 28.2 ± 5.9 30.0 ± 5.4 0.020 d *
Engagement with life (EwL) [16, 80]
(x¯ ± s)
70.1 ± 10.8 72.3 ± 13.1 69.5 ± 9.9 0.016 d *
4. Psychosocial Factors
Brief Resilient Coping Scale (BRCS) [4, 20]
(x¯ ± s)
16.3 ± 3.0 15.5 ± 3.1 16.5 ± 3.0 0.018 d *
Low [4, 13)
Intermediate [13, 17]
High (17, 20]
24 (11.3) 10 (19.2) 14 (8.7) 0.075 c
104 (48.8) 26 (50.0) 78 (48.4)
85 (39.9) 16 (30.8) 69 (42.9)
5. Health Problems
Hypertension
Yes [systolic BP > 140 mmHg or diastolic BP > 90 mmHg]
No [systolic BP ≤ 140 mmHg and diastolic BP ≤ 90 mmHg]
126 (60.0) 38 (76.0) 88 (55.0) 0.008 c **
84 (40.0) 12 (24.0) 72 (45.0)
Hypercholesterolemia
Yes [Total > 200 mg/dL or LDL >100 mg/dL or HDL ≤ 35–40 mg/dL]
No [Total ≤ 200 mg/dL or LDL ≤ 100 mg/dL or HDL > 35–40 mg/dL]
94 (44.8) 29 (55.8) 65 (41.1) 0.078 c
116 (55.2) 23 (44.2) 93 (58.9)
Diabetes
Yes [Blood glucose > 126 mg/dL or HbA1c > 6.5%]
No [Blood glucose ≤ 126 mg/dL and HbA1c ≤ 6.5%]
50 (23.5) 18 (34.6) 32 (19.9) 0.038 c *
163 (76.5) 34 (65.4) 129 (80.1)
ERICE Scale [1, 84]
(x¯ ± s)
28.4 ± 17.4 36.9 ± 15.9 26.0 ± 17.1 <0.001 d ***
Low [1, 5) 1 (0.5) 0 (0.0) 1 (0.6) 0.002 b **
Mild [5, 9] 37 (17.9) 3 (6.4) 34 (21.2)
Moderate [10, 14] 18 (8.7) 1 (2.1) 17 (10.6)
Moderate–high [15, 19] 17 (8.2) 2 (4.3) 15 (9.4)
High [20, 29] 42 (20.3) 8 (17.0) 34 (21.2)
Very high [30, 80] 92 (44.4) 33 (70.2) 59 (36.9)
Dependent chronic pain [0, 10]
(x¯ ± s)
3.4 ± 2.8 4.2 ± 2.7 3.2 ± 2.8 0.013 d *
No pain [0] 54 (26.0) 5 (10.0) 49 (31.0) 0.018 b *
Mild [1, 3] 57 (27.4) 17 (34.0) 40 (25.3)
Moderate [4, 6] 65 (31.2) 19 (38.0) 46 (29.1)
Severe [7, 8] 23 (11.1) 5 (10.0) 18 (11.4)
Unbearable [9, 10] 9 (4.3) 4 (8.0) 5 (3.2)
6. Lifestyle
BMI
(x¯ ± s)
27.2 ± 4.1 28.3 ± 3.8 26.8 ± 4.1 0.017 a *
Normal weight [18.5, 25) 61 (29.6) 8 (16.3) 53 (33.9) 0.046 c *
Overweight [25, 30) 96 (46.6) 26 (51.3) 70 (44.6)
Obese [30, +∞) 49 (23.8) 15 (30.6) 34 (21.7)
Retired
Yes
No
145 (68.7) 48 (94.1) 97 (60.6) <0.001 b ***
66 (31.3) 3 (5.9) 63 (39.4)
Cognitive Reserve Questionnaire (CRC) [0, 25]
(x¯ ± s)
10.3 ± 5.1 8.2 ± 5.1 11.0 ± 5.0 <0.001 d ***
Low [0, 6] 55 (25.9) 22 (43.1) 33 (20.5) 0.010 b *
Intermediate–low [7, 9] 46 (21.7) 11 (21.6) 35 (21.7)
Intermediate–high [10, 14] 65 (30.7) 12 (23.5) 53 (32.9)
High [15, 25] 46 (21.7) 6 (11.8) 40 (24.8)
STOP–Bang Questionnaire [0, 8]
(x¯ ± s)
3.1 ± 1.4 3.5 ± 1.3 3.0 ± 1.5 0.005 d **
Low [0, 2] 81 (38.0) 13 (25.0) 68 (42.2) 0.075 b
Intermediate [3, 4] 97 (45.5) 28 (53.8) 69 (42.9)
High [5, 8] 35 (16.4) 11 (21.2) 24 (14.9)

Variables associated with cognitive impairment. a: t-test for comparison of two independent means (one-sided); b: Fisher’s exact test; c: Chi-squared test; d: Wilcoxon test for two independent means (one-sided); †: p-value < 0.1; *: p-value < 0.05; **: p-value < 0.01; ***: p-value < 0.001.