Table 2.
Logistic regression for kidney function pattern and associated inpatient mortality
| Univariable |
Multivariable |
|||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Kidney diagnosis | ||||||
| Normal | 0.63 | 0.62–0.65 | < 0.001 | 0.75 | 0.73–0.78 | < 0.001 |
| AKI | 4.95 | 4.84–5.07 | < 0.001 | 2.40 | 2.32–2.48 | < 0.001 |
| CKD | – | – | – | – | – | – |
| AKI on CKD | 2.50 | 2.44–2.57 | < 0.001 | 1.66 | 1.60–1.72 | < 0.001 |
| Age per year | 1.02 | 1.02–1.02 | < 0.001 | 1.02 | 1.02–1.02 | < 0.001 |
| Female Sex | 0.96 | 0.94–0.97 | < 0.001 | 0.93 | 0.92–0.95 | < 0.001 |
| Race | ||||||
| Caucasian | – | – | – | – | – | – |
| African-American | 1.04 | 1.01–1.06 | 0.001 | 1.06 | 1.03–1.09 | < 0.001 |
| Hispanic | 0.85 | 0.83–0.86 | < 0.001 | 1.00 | 0.98–1.03 | 0.90 |
| Asian | 1.28 | 1.23–1.34 | < 0.001 | 1.23 | 1.16–1.29 | < 0.001 |
| Other | 1.01 | 0.99–1.02 | 0.55 | 0.99 | 0.97–1.01 | 0.38 |
| Hepatitis C | 0.66 | 0.65–0.67 | < 0.001 | 0.95 | 0.93–0.97 | < 0.001 |
| EtOH-related | 0.79 | 0.77–0.80 | < 0.001 | 1.08 | 1.06–1.10 | < 0.001 |
| Diabetes mellitus | 0.46 | 0.45–0.47 | < 0.001 | 0.65 | 0.63–0.66 | < 0.001 |
| Hospital location | ||||||
| Metropolitan city center | – | – | – | – | – | – |
| Metropolitan county | 0.98 | 0.96–1.00 | 0.04 | 1.00 | 0.98–1.03 | 0.75 |
| Large county | 1.00 | 0.98–1.02 | 0.89 | 1.11 | 1.09–1.14 | < 0.001 |
| Medium county | 1.02 | 0.99–1.04 | 0.14 | 1.20 | 1.16–1.23 | < 0.001 |
| Micropolitan county | 1.06 | 1.04–1.09 | < 0.001 | 1.27 | 1.23–1.31 | < 0.001 |
| Other | 1.07 | 1.04–1.10 | < 0.001 | 1.30 | 1.25–1.34 | < 0.001 |
| Infectious status | ||||||
| None | – | – | – | – | – | – |
| Infection | 1.39 | 1.37–1.42 | < 0.001 | 1.07 | 1.05–1.09 | < 0.001 |
| Sepsis | 8.88 | 8.75–9.01 | < 0.001 | 2.14 | 2.09–2.18 | < 0.001 |
| Shock | 14.44 | 14.21–14.67 | < 0.001 | 2.53 | 2.46–2.59 | < 0.001 |
| Mechanical ventilation | 15.92 | 15.68–16.15 | < 0.001 | 6.07 | 5.95–6.20 | < 0.001 |
| Year of admission | ||||||
| 2007–2008 | – | – | – | – | – | – |
| 2009–2010 | 0.94 | 0.92–0.95 | < 0.001 | 0.80 | 0.78–0.82 | < 0.001 |
| 2011–2012 | 0.86 | 0.84–0.88 | < 0.001 | 0.68 | 0.67–0.70 | < 0.001 |
| 2013–2014 | 0.85 | 0.83–0.86 | < 0.001 | 0.61 | 0.60–0.62 | < 0.001 |
| Decompensated cirrhosis | 2.17 | 2.14–2.21 | < 0.001 | 1.41 | 1.39–1.44 | < 0.001 |
| RRT | 2.52 | 2.48–2.57 | < 0.001 | 1.14 | 1.09–1.19 | < 0.001 |
| Kidney pattern and dialysis# | ||||||
| Normal | – | – | – | – | – | – |
| AKI | 2.62 | 2.47–2.75 | < 0.001 | 1.39 | 1.30–1.48 | < 0.001 |
| CKD | Ref | Ref | Ref | Ref | Ref | Ref |
| AKI on CKD | 1.73 | 1.63–1.83 | < 0.001 | 1.10 | 1.03–1.17 | 0.005 |
AKI acute kidney injury, CKD chronic kidney disease, AKI on CKD acute kidney injury on chronic kidney disease, EtOH alcohol-related disease, RRT renal replacement therapy
#
This is the interaction term between variables