Table 3.
The mean log2-fold change of blood plasma and serum metabolites (PA over control) levels (Fig. S1, Fig. S2)
| Biofluid | Metabolite | Mean log2-fold change (PA/control) | In PA children |
|---|---|---|---|
| Plasma | Alanine | 0.019 | ↑ |
| Glucose | 0.011 | ↑ | |
| Glycerol | 0.382 | ↑ | |
| Lactic acid | − 0.071 | ↓ | |
| Leucine | 0.049 | ↑ | |
| GlcNAc | − 0.435 | ↓ | |
| Serum | Glucose | 0.021 | ↑ |
| Glycerol | 0.084 | ↑ | |
| Glycine | − 0.002 | ↓ | |
| Myo-inositol | 0.008 | ↑ | |
| Serine | 0.027 | ↑ |
Metabolites’ fold changes are presented using the calculated metabolite peak area in NMR spectra of PA and control group (Δp-PA/control)
↑Increased in children with PA
↓Decreased in children with PA