Fig. 6. Addition of new HLC transcriptomes to the HLCompR web application.

a Principal component analysis on query datasets. Circles indicate the cell or tissue types in the query datasets that are also present in the training dataset (e.g., PHH, liver, HepG2, fetal hepatocyte, and PSC) or the HepaRG samples in Gupta⁷⁴ dataset. HLCompR compatibility is categorized based on the comparability of PHHs and liver tissue between the query and training datasets. b Cell/tissue classification heatmap of representative training samples and query samples. c Gene regulatory network status of liver and embryonic stem cells (ESCs) of all PHH, liver, HepG2, and PSC samples from training dataset and query dataset presented as mean ± standard deviation. Source data are provided in Supplementary Data 8.