Table 8.

21 volatile compounds identified by GC–MS from dichloromethane crude extract of Streptomyces sp. E23-4 OM883990 strain. RT: Retention time; M.W.: Molecular Weight.

RT (time)	Area (%)	M.W. (g/mol)	Molecular formula	Coompound name	Reported bioactivity
9.197	3.37	94.20	C2H6S2	Disulfide, dimethyl	Antioxidant, Antifungal, Analgesic effect94–96
9.366	0.28	85.13	C3H3NS	1,3-thiazole	Antibacterial activity97, anti-inflammatory activity98 , antitumor and cytotoxic activity99
9.467	1.25	94.10	C6H5OH	Phenol	Antimicrobial activity, antibacterial activity, and antioxidant activity100
9.580	0.30	112.08	C4H4N2O2	Maleic hydrazide	Anti-tumorigenic effect101
10.267	0.18	126.11	C6H6O3	Methyl 2-furoate	Antifungal102
10.583	0.67	126.11	C6H6O3	Maltol	Antioxidant, Anti-inflammatory, and Antitumor103
10.955	0.76	144.12	C6H8O4	4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-	Antioxidant104
12.746	0.80	136.14	C8H8O2	Benzeneacetic acid	Antifungal, Antimicrobial, and Antioxidant70–72
19.767	0.40	222.24	C12H14O4	Diethyl Phthalate	Antimicrobial, Antifungal105
24.962	1.57	283.36	C15H25NO4	l-Proline, N-allyloxycarbonyl-, isohexyl ester	Not yet reported
26.866	3.22	409.6	C25H47NO3	l-Leucine, N-cyclopropylcarbonyl-, pentadecyl ester	Antibacterial106
27.328	6.21	154.3	C4H10S3	Diethyl trisulphide	Antimicrobial62
27.553	1.83	451.68	C27H49NO4	l-Proline, N-allyloxycarbonyl-, octadecyl ester	Not yet reported
34.968	2.77	244.29	C14H16N2O2	Pyrrolo [1, 2-a] pyrazine-1, 4-dione, hexahydro-3-(phenylmethyl)	Antifungal, Antioxidant, and Anibacterial65–67
47.307	3.54	323.41	C18H17N3OS	Acetamide, N-[4-[2-[(3-methylphenyl) amino]-4-thiazolyl]phenyl]-	Anticancer activity107
47.454	4.76	323.39	C20H21NO3	Indole-3-carboxylic acid, 5-methoxy-2-methyl-1-(3-methylphenyl)-, ethyl ester	Anticonvulsant, Antioxidant, Anticancer, Antibacterial and Anti-inflammatory Antitubercular, Antimalarial Resistance mediator against necrotrophic pathogens 63,64
47.961	0.22	222.40	C13H22OSi	Thymol, TMS derivative	Anibacterial, Antifungal, Antioxidant, Anticancer24,108,109
48.524	0.36	264.46	C13H20N2SSi	1, 2-Benzisothiazol-3-amine, TBDMS derivative	Antifungal, Antioxidant and Anti-proliferative68,69
48.829	0.36	222.40	C13H22OSi	Thymol, TMS derivative	Anibacterial, Antifungal, Antioxidant, Anticancer24,108,109
48.975	0.21	222.47	C12H22Si2	1,2-Bis (trimethylsilyl) benzene	Antimicrobial, Antioxidant, Anibacterial110
49.381	0.44	207.27	C15H13N	Benzo[h]quinoline, 2,4-dimethyl-	anti-inflammatory111, antioxidant112, anti-HIV113, antifungal114, treatment of neurodegenerative diseases115, antitubercular116, and anticancer117