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. 2022 Oct 14;12:17255. doi: 10.1038/s41598-022-21311-3

Table 1.

Baseline data.

Demographics
Age (mean/SD) 64/± 13
Male (n/%) 43/79.6%
Comorbidities
Cardiovascular disease (n/%) 10/18.5%
Asthma/COPD (n/%) 6/11.1%
Diabetes (n/%) 14/25.9%
Obesity (n/%) 19/35.2%
Hypertension (n/%) 21/38.9%
Previous stroke (n/%) 3/5.6%
Traumatic brain injury (n/%) 1/1.9%
Hydrocephalus/chronic intracranial hypertension (n/%) 0/0%
Pregnancy (n/%) 1/1.9%
Known allergy to sonographic gel 0/0%
Treatments
Vasopressors (n/%) 38/70.4%
Inotropic drugs (n/%) 6/11.1%
Ventilator mode, pressure support (n/%) 25/46.3%
Ventilator mode, pressure control (n/%) 29/53.7%
PEEP (mean/SD) 11.3/± 2.9
Pressure support/pressure control (mean/SD) 13.8/± 4.5
Peak airway pressure (mean/SD) 25/± 5
Accumulated time of prone positioning (hours/SD) 38/± 34
Other baseline data
PFI (ratio of pO2 in kPa to FiO2) at time of ONSD/ED measurement (mean/SD) 19/± 6
pCO2 (kPa) at time of ONSD/ED measurement (mean/SD) 6.6/± 1.5
AKI at time of ONSD/ED measurement (n/%) 10/18.5%
ICU day of ONSD/ED measurement (median/interquartile range) 6/4 to 13

SD standard deviation, n numbers, COPD chronic obstructive pulmonary disease, ONSD/ED optic nerve sheath diameter divided by eyeball diameter, PFI ratio of partial pressure of oxygen (kPa) in arterial blood divided by fraction of inspired oxygen, pCO2 partial pressure of carbon dioxide (kPa) in arterial blood, AKI acute kidney injury, ICU intensive care unit.