TABLE 1.
Clinical information for individuals with HIV expressing RTF on the surface of peripheral blood T lymphocytesa
| Individual | % of T lymphocytes expressing high levels of RTF | % of CD4+/CD8+ T lymphocytes | Absolute CD4 count | Viral load | Admission status |
|---|---|---|---|---|---|
| 1 | 76.4 | 22.0/47.2 | 170 | 340.0 | In (pneumonia) |
| 2 | 75.0 | 13.0/67.6 | 143 | ND | Out |
| 3 | 65.2 | 0.9/18.4 | 68 | ND | Out |
| 4 | 60.3 | 4.6/79.5 | 63 | ND | Out |
| 5 | 48.2 | 17.0/62.2 | 187 | ND | Out (h/o hepatitis C) |
| 6 | 47.3 | 6.8/10.5 | 246 | ND | Out |
| 7 | 47.2 | 37.6/38.9 | 350 | ND | Out |
| 8 | 45.2 | 27.5/65.1 | 447 | 8.2 | In (peritonitis) |
| 9 | 42.9 | 2.3/73.1 | 40 | 24.7 | Out (h/o hepatitis C) |
| 10 | 36.1 | 41.5/33.3 | 1,157 | ND | Out |
| 11 | 35.2 | 30.0/36.7 | 317 | 15.0 | Out |
| 12 | 34.3 | 60.0/21.0 | 295 | 2.1 | Out (influenza-like symptoms) |
| 13 | 32.1 | 0.2/52.5 | 2 | ND | In (cytomegalovirus retinitis) |
| 14 | 21.8 | 18.7/62.5 | 513 | ND | Out |
| 15 | 20.4 | 39.0/44.2 | 290 | ND | Out |
| 16 | 18.5 | 36.8/41.3 | 852 | ND | Out |
| 17 | 18.1 | 26.6/51.0 | 528 | ND | Out (influenza-like symptoms) |
| 18 | 16.0 | 25.9/49.7 | 356 | 5.9 | Out |
| 19 | 13.2 | 40.2/33.1 | 571 | 1.0 | Out |
| 20 | 11.5 | 21.5/60.3 | 465 | <0.5 | Out (influenza-like symptoms) |
| 21 | 10.2 | 0.9/26.2 | 23 | 40.0 | Out |
| 22 | 9.9 | 13.9/71.0 | 182 | 8.1 | Out |
| 23 | 9.1 | 20.4/64.8 | 212 | ND | Out |
| 24 | 6.1 | 27.8/51.3 | 535 | ND | Out |
| 25 | 2.9 | 18.8/42.5 | 221 | ND | Out |
The percentages of CD4+ and CD8+ T lymphocytes present in the lymphocyte population of the individuals evaluated were determined by flow cytometric analysis and with appropriately conjugated antibodies. Absolute CD4 counts were determined at the same time that RTF expression was evaluated and are expressed as the number of cells per microliter of blood. In most cases, viral load determinations were also made at the same time that RTF expression was evaluated. Viral load determinations are expressed as the number of HIV RNA copies per milliliter of blood (103). ND, not determined. Admission status refers to in- or outpatient and was recorded when RTF expression was evaluated. When known, the reason for the individual’s stay in or visit to the hospital is indicated in parentheses. h/o, history of. The majority of evaluated individuals were asymptomatic outpatients visiting the hospital for routine evaluation.