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. 2022 Oct 14;5(10):e2236626. doi: 10.1001/jamanetworkopen.2022.36626

Table 2. Select Clinical Outcomes According to Predominant or Uniform Type I and Type II Morphologic Subtype.

Characteristic Predominant morphologic subtype Uniform morphologic subtype
Type I (n = 57) Type II (n = 37) P value Type I (n = 48) Type II (n = 23) P value
Response to NACT, No. (%)
Excellent NA NA NA 17 (63) 3 (38) .25
Poor NA NA 2 (7) 2 (25)
Nonclassifiable NA NA 8 (30) 3 (38)
PIV, No. (%)
<8 27 (47) 25 (68) .05 22 (46) 19 (83) .004
≥8 30 (53) 12 (32) 26 (54) 4 (17)
Postlaparoscopy treatment, No. (%)
NACT 32 (56) 18 (49) .48 27 (56) 8 (35) .09
pTRS 25 (44) 19 (51) 21 (44) 15 (65)
TRS, No. (%)
Not performed 4 (7) 2 (5) .84 4 (8) 1 (4) .28
Primary 25 (44) 19 (51) 21 (44) 15 (65)
Interval 28 (49) 16 (43) 23 (48) 7 (30)
Operative time, min
No. 52 35 .02 43 20 .03
Mean (SD) 330 (110) 400 (133) 333 (113) 408 (130)
Median (range) 326 (140-711) 393 (222-717) 322 (140-711) 396 (222-717)
Estimated blood loss, mL
No. 52 35 .001 43 22 .006
Mean (SD) 406 (492) 717 (673) 415 (527) 639 (559)
Median (range) 250 (50-2250) 500 (75-3000) 200 (50-2250) 475 (75-2500)
TRS status, No. (%)
Complete 42 (81) 29 (83) .60 34 (79%) 18 (82) .64
Optimal 4 (8) 4 (11) 4 (9%) 3 (14)
Suboptimal 6 (12) 2 (6) 5 (12%) 1 (5)
Length of stay, d
No. 52 35 .03 43 22 .08
Mean (SD) 6.1 (6.7) 7.8 (7.6) 6.4 (7.2) 6.8 (4.8)
Median (range) 4.0 (0.0-34.0) 6.0 (2.0-43.0) 4.0 (0.0-34.0) 6.0 (2.0-25.0)

Abbreviations: NA, not applicable; NACT, neoadjuvant chemotherapy; PIV, predictive index value; pTRS, primary tumor reductive surgery; TRS, tumor reductive surgery.