Table 2.
Univariate analysis for EBER * positivity.
| Variable | EBER Positive | EBER Negative | p Value |
|---|---|---|---|
| Gender Male Female |
n (%) 83 (77.6%) 24 (22.4%) |
n (%) 13 (76.5%) 4 (23.5%) |
0.920 |
| Race/Skin color White Brown/Black |
83 (79.0%) 22 (21.0%) |
12 (75.0%) 4 (25.0%) |
0.746 |
| Clinical Stage I II III IVa IVb |
2 (1.9%) 7 (6.6%) 27 (25.5%) 56 (52.8%) 14 (13.2%) |
0 (0%) 1 (5.9%) 4 (23.5%) 10 (58.8%) 2 (11.8%) |
0.976 |
| PD-L1 ** Positive Negative |
63 (61.2%) 40 (38.8%) |
4 (23.5%) 13 (76.5%) |
0.004 |
| Alcoholism Habits No Yes |
63 (63.6%) 36 (36.4%) |
6 (35.3%) 11 (64.7%) |
0.028 |
| Smoking Habits Never Acive/Former smoker |
61 (62.9%) 36 (37.1%) |
3 (18.7%) 13 (81.3%) |
0.001 |
| Comorbidity Absent Present |
69 (64.5%) 38 (35.5%) |
6 (35.3%) 11 (64.7%) |
0.022 |
| Non-keratinizing SCC 1
Undifferentiated Differentiated |
71 (67.0%) 35 (33.0%) |
1 (7.7%) 12 (92.3%) |
<0.001 |
* EBER: Epstein–Barr-virus-encoded small RNAs; ** PD-L1: programmed cell death ligand-1; 1 SCC: squamous cell carcinoma.