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. 2022 Oct 6;23(19):11894. doi: 10.3390/ijms231911894

Figure 1.

Figure 1

NOD2 ligand co-administration does not aggravate allergen-induced airway cell recruitment, humoral response, and AHR. (a) Protocol of dog-induced experimental AAI, with or without NOD2 agonist co-administration. (b) BAL cell counts in control (PBS and MDP) and challenged (dog and dog/MDP) mice. (c) ELISA measurement of total IgE and dog-specific IgE (as titers) in sera. (d) AHR in control and challenged mice. Data are presented as mean ± SEM (n = 7–22 mice per group, or n = 5–11 mice per group for AHR). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 versus PBS or indicated column; + p < 0.05, ++ p < 0.01 versus MDP. Kruskal–Wallis test for all, except AHR, which is 2-way ANOVA.