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. 2022 Oct 6;23(19):11894. doi: 10.3390/ijms231911894

Figure 6.

Figure 6

MDP does not aggravate the formation of iBALT. Representative microphotographs and quantification of iBALT. (a) Numbers and surface area (number of grid squares) of iBALT. (b) Levels of total IgA and dog-specific IgG1 (as titers) in BAL. (c–e) Immunohistochemistry staining of FDC (c), B (d), and T (e) cells and counts and surface area per iBALT. Scale bars: 100 μm. Positive cells are stained in red. Black arrows show staining of interest. Data are presented as mean ± SEM (n = 4–6 mice per group, with 3 to 9 different lung sections analyzed per mouse, for histology, and n = 9–18 mice per group for Ig). * p < 0.05, ** p < 0.01, **** p < 0.0001 versus PBS or MDP. Kruskal–Wallis test for all.