Table 1.

Chronic binge-like ethanol drinking reduces expression of circadian genes in the NAc and SCN of female HDID-1 mice in Experiment 1. Descriptive statistics for the NAc, VTA, and SCN.

Descriptive Statistics for Experiment 1
NAc	Main effects	Clock	Npas2	Bmal1	Per1	Per2	Per3
	Fluid Type	F(1, 80) = 21.61	F(1, 80) = 18.01	F(1, 80) = 0.03	F(1, 80) = 34.67	F(1, 80) = 7.03	F(1, 80) = 5.28
	p-value	****	****	ns	****	**	*
	ZT	F(7, 80) = 2.72	F(7, 80) = 3.22	F(7, 80) = 7.33	F(7, 80) = 3.72	F(7, 80) = 27.64	F(7, 80) = 6.68
	p-value	*	**	****	**	****	****
	Interaction	F(7, 80) = 2.83	F(7, 80) = 1.73	F(7, 80) = 4.92	F(7, 80) = 1.37	F(7, 80) = 2.74	F(7, 80) = 1.73
	p-value	*	ns	***	ns	*	ns
VTA	Main effects	Clock	Npas2	Bmal1	Per1	Per2	Per3
	Fluid Type	F(1, 74) = 0.10	F(1, 74) = 0.25	F(1, 74) = 0.08	F(1,70) = 1.68	F(1,73) = 1.11	F(1, 74) = 1.85
	p-value	ns	ns	ns	ns	ns	ns
	ZT	F(7, 74) = 0.35	F(7, 74) = 0.86	F(7, 74) = 1.67	F(7,70) = 1.62	F(7,73) = 0.44	F(7, 74) = 0.85
	p-value	ns	ns	ns	ns	ns	ns
	Interaction	F(7, 74) = 1.47	F(7, 74) = 0.50	F(7, 74) = 1.22	F(7,70) = 1.62	F(7,73) = 0.44	F(7, 74) = 0.89
	p-value	ns	ns	ns	ns	ns	ns
SCN	Main effects	Clock	Npas2	Bmal1	Per1	Per2	Per3
	Fluid Type	F(1, 76) = 2.78	F(1, 74) = 2,74	F(1, 76) = 1.71	F(1, 74) = 9.08	F(1, 76) = 12.22	F(1, 75) = 2.08
	p-value	ns	ns	ns	**	***	ns
	ZT	F(7, 76) = 2.27	F(7, 74) = 1.32	F(7, 76) = 3.15	F(7, 74) = 3.96	F(7, 76) = 5.87	F(7, 80) = 4.98
	p-value	*	ns	**	***	****	***
	Interaction	F(7, 76) = 0.48	F(7, 76) = 0.93	F(7, 80) = 1.01	F(7, 74) = 3.66	F(7, 76) = 0.84	F(7, 80) = 0.78
	p-value	ns	ns	ns	**	ns	ns

ns = nonsignificant; * = p < 0.05; ** = p < 0.01; *** = p < 0.001; **** < 0.0001.