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. 2022 Oct 6;23(19):11850. doi: 10.3390/ijms231911850

Figure 1.

Figure 1

Advances in MAFLD human models. (Top) Timeline of representative MAFLD human model studies [41,42,43,44,45,46,47,48,49,50,51,52], which reflect how different cell types and the inducers of MAFLD (tables below) have been employed to create increasingly complex model systems. This includes the use of various cell culture platforms such as organoid culture systems as well as microfluidics. (Bottom) Tables listing the commonly used cell types for modeling different liver cells and molecules used in various studies to induce MAFLD phenotype (inducers).