List of Abbreviations Used
Abbreviation	Full Name	Gene Name	Full Name
2D	2-dimensional	ABCB11	ATP Binding Cassette subfamily B member 11
3D	3-dimensional	ABCB4	ATP Binding Cassette subfamily B member 4
AAA	Aromatic Amino Acid	ALB	Albumin
BCAA	Branched-Chain Amino Acid	APOC3	Apolipoprotein C3
BMP-8B	Bone Morphogenetic Protein-8B	CK7	Keratin 7
CCL	C-C motif Chemokine Ligand	CK8	Keratin 8
CDK	Cyclin-dependent Kinase	CLEC4F	C-type lectin domain family 4 member F
CKD	Chronic Kidney Disease	CYP3A4	Cytochrome P450 family 3 subfamily A member 4
CTRP9	C1q/TNF-Related Protein 9	FGF19	Fibroblast Growth Factor 19
CVD	Cardiovascular Disease	GCKR	Glucokinase Regulator
CXCL	Chemokine (C-X-C motif) Ligand	HNF4A	Hepatocyte Nuclear Factor 4 alpha
DAMP	Death-associated Molecular Pattern	HSD17B13	Hydroxysteroid 17-beta Dehydrogenase 13
DNL	De Novo Lipogenesis	MBOAT7	Membrane-Bound O-acyltransferase Domain-Containing 7
ECM	Extra-cellular Matrix	NR0B2	Nuclear Receptor subfamily 0 group B member 2
ER	Endoplasmic Reticulum	PNPLA3	Patatin-like Phospholipase Domain-Containing 3
FFA	Free Fatty Acid	TM6SF2	Transmembrane 6 Superfamily Member 2
FXR	Farnesoid X Receptor
GLP1R	Glucagon-Like Peptide 1 Receptor
GWAS	Genome-wide Association Studies
HCC	Hepatocellular Carcinoma
HLC	Hepatocyte-like Cell
hLiMT	Human Liver Microtissues
HSC	Hepatic Stellate Cell
IL	Interleukin
iPSC	Induced Pluripotent Stem Cell
IRS2	Insulin Receptor Substrate-2
LSEC	Liver Sinusoidal Endothelial Cell
MAFLD	Metabolic (Dysfunction) Associated Fatty Liver Disease
MMP	Matrix Metalloproteinase
NAFLD	Non-alcoholic Fatty Liver Disease
NASH	Non-alcoholic Steatohepatitis
NEFA	Non-esterified Fatty Acid
NK	Natural Killer
NPC	Non-parenchymal Cell
OA	Oleic Acid
OCA	Obeticholic Acid
P3NP	N-terminal pro-peptide of collagen type III
PA	Palmitic Acid
PAMP	Pathogen-associated Molecular Pattern
PCTS	Precision-Cut Tissue Slice
PDGF	Platelet-Derived Growth Factor
PHH	Primary Human Hepatocyte
PI3K	Phosphatidylinositol-3-OH Kinase
PKC	Protein Kinase C
PSC	Pluripotent Stem Cell
ROS	Reactive Oxygen Species
SA	Stearic Acid
SGLT2	Sodium–Glucose Cotransporter-2
SNP	Single-Nucleotide Polymorphism
T2DM	Type II Diabetes Mellitus
TH17	T helper 17 (TH17) cells
TGF	Transforming Growth Factor
TNF	Tumor Necrosis Factor
Treg	Regulatory T cells
VLDL	Very-low-density lipoprotein.
α-SMA	Alpha-Smooth Muscle Actin