BBB	Blood–brain barrier
BC	Breast cancer
BCBM	Breast cancer brain metastasis
bHER2-ATC	Biparatopic anti-HER2 antibody-tubulysin conjugate
BMs	Brain metastases
BMsBC	Brain metastases breast cancer
BRCA1	Breast cancer type 1
cANGPTL4	Angiopoietin-like 4 fibrinogen-like domain
CNS	Central nervous system
COX-2/MMP1	Cyclooxygenase 2/Matrix metalloproteinase 1
CXCR4	CXC chemokine receptor 4
DTI	Diffusion tensor imaging
ER	Estrogen
GPA	Graded prognostic assessment
HDACs	Histone deacetylases
HER2	Human epidermal growth factor receptor 2
IGF1R	Type 1 insulin-like growth factor receptor
LncRNA	Long noncoding RNA
MBC	Metastatic breast cancer
MEF2	Myocyte enhancer factor 2
miRNAs	MicroRNAs
MMP-2	Matrix metalloproteinase-2
mTOR	Mammalian target of rapamycin
NPNT	Nephronectin
PCI	Prophylactic cranial irradiation
PDGF	Platelet-derived growth factor
PDGFRβ	Platelet-derived growth factor receptor-beta
PD-1	Programmed death receptor 1
PDXs	Patient-derived xenografts
PI3K/AKT	Phosphatidylinositol-3-kinase/Protein kinase B
PR	Progesterone
RRM2	Ribonucleotide reductase M2
SRS	Stereotactic radiosurgery
T-DM1	Trastuzumab emtansine
TGLI1	Truncated glioma-associated oncogene homolog 1
TNBC	Triple-negative breast cancer
VEGF	Vascular endothelial growth factor
WBRT	Whole-brain radiation targeting