Table 1.

Drugs inducing major types of chronic hepatocellular or cholestatic liver injury.

Autoimmune-like Drug-Induced Liver Injury [20,30,31,32]	Hepatic Steatosis and/or NASH [30,33,34,35,36]	Phospholipidosis/Hepatocellular Deposits Cytoplasmic Inclusions [35,36,37,38,39]	Cholestasis or Vanishing Bile Duct Syndrome [22,30,32,36,40,41,42]
α-methyldopa Allopurinol Benzarone Chlorpromazine Dantrolene Diclofenac Dihihydralazine Fluoxetine Halothane Indomethacin Interferon β Isoniazid Minocycline Nitrofurantoin Phenytoin Statins: Atorvastatin, Rosuvastatin, Simvastatin Sulfonamide Terbinafine Tienilic acid TNF-α antagonists: Adalimumab, Infliximab, Etanercept	5-fluorouracil Amineptine Acetylsalycilic Amiodarone Apo-B inhibitors: Mipomersen, Limitapide Doxycycline Fialuridine Glucocorticoids (Dexamethasone) Ibuprofen Irinotecan Methotrexate Nifedipine NRTIs: Zidovudine, Didanosine, Stavudine Perhexiline Tamoxifen Tetracycline Tianeptine Valproic acid	Amiodarone Amikacin Amitriptyline Chlorpromarizine Citalopram Clomipramine Clozapine Desipramine Fluoxetine Haloperidol Hydroxyzine Imipramine Ketoconazole Maprotiline Perhexiline Sertraline Tamoxifen Thioridazine Tilorone Zimelidine	Anabolic-androgenic steroids Amitriptyline Amoxicillin–clavulanic acid Azathioprine Azithromycin Bosentan Captopril Carbamazepine Chlorpromazine Cyclosporine Erythromycin Ethynyl estradiol (oral contraceptives) Flucloxacillin Griseofulvin Haloperidol Itraconazole Levofloxacin Nimesulide Phenytoin Terbinafine

NRTIs: nucleoside reverse transcriptase inhibitors.