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. 2022 Sep 24;23(19):11270. doi: 10.3390/ijms231911270

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Percentage of biofilm reduction in pre-formed P. aeruginosa biofilms using commercialized concentrations of three antiseptics (sodium hypochlorite (A, pink), PHMB (B, blue) and octenidine (C, red)) in BHI and CWM. In vitro automatized debridement left a mean of 12% of biofilm in the microfluidic channel before antiseptic treatment after 72 h of culture. The mean percentage of biofilm after in vitro automatized debridement and before antiseptic treatment is represented by the dashed line. Samples were tested in six independent experiments. Results are presented as the mean ± standard deviation. Statistics were performed using a t-test using the R^® software version 4.0.2 to compare the efficiency of antiseptics on biofilms after in vitro automatized debridement. *, p < 0.1; ** p < 0.01.