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. 2022 Oct 2;23(19):11662. doi: 10.3390/ijms231911662

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Physical characterization of RTLs produced by extrusion. (A) Table of liposome characteristics as measured by NTA at 25 °C. (B–C) Representative NTA plots the particle/mL vs. diameter for SN-38 loaded RTLs. (D) Cryo-TEM images of RTL liposomes containing PE:DSPC:Chol:DSPE-mPEG (Molar ratio 1:0.5:0.5:0.075).