Figure 4.

Radiation release of ICG-loaded RTLs. (A) Self-quenching ICG loaded liposomes. (B) Representative lateral IVIS images of ICG associated fluorescence 4 h post injection and immediately after radiation. (C) Average radiant efficiency in the tumor region over the course of 24 h post radiation. (D) Representative ex vivo IVIS imaging of ICG associated fluorescence in vital organs and tumor at 24 h post radiation. (E) Average radiant efficiency of vital organs and tumor. Data presented as mean ± SEM; n = 5–6. One-way ANOVA with Tukey post hoc for comparison of all tissues to tumor for each group (* p < 0.05, ** p < 0.01).