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. 2022 Sep 29;23(19):11489. doi: 10.3390/ijms231911489

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Analysis of enriched domains in host-pathogen PPIs. (A) Bar plot representation of the 10 most enriched domains for human proteins (left). The tridimensional structure of the most enriched human domain, IPR001101, is displayed. Representative GO enriched terms for host domains are displayed on the right. (B) Bar plot representation of the 10 most enriched observed domains for bacterial proteins (left). The tridimensional structure of the two most enriched bacterial domains, IPR025875 and IPR019931, are also displayed. Representative GO enriched terms for bacterial domains are displayed on the right. In all cases, the GO term frequency is displayed on the x-axis and the GO term on the y-axis. Colors represent adjusted p-values for each GO term as calculated by dcGO [31].