Figure 9.
Analysis of complexes between IpaH and sspH2 with ubiquitin UBA52. (A) Structure of UBA52 and sspH2 showing the degree of sequence conservation. The conservation scale is displayed at the bottom of the figure. (B) Residue contact network between UBA52 and sspH2 showing several contact signatures. (C) Blast search results using the ubiquitin-protein ligase domain as the query sequence. Newly identified domains are highlighted by brown boxes. (D) Predicted structures of selected proteins using Alphafold [26].