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. 2022 Oct 4;23(19):11757. doi: 10.3390/ijms231911757

Figure 1.

Figure 1

Fluorescence microscopy of CD20 (red) and CXCR4 (green) double staining of the eyes in the PDX PCNSL vs. PDX SCNSL group. (A–C) show recordings of the choroid, (D–F) of the retina and (G–I) of the ciliary body (marked with *). (A) shows the choroid infiltrated with CD20-positive primary CNS lymphoma cells (PCNSL+), which additionally express CXCR4 (triangles). (D,G) show retina and ciliary body infiltrated with CD20-positive cells (PCNSL+) without co-expression. Neither CD20- nor CXCR4-positive cells were found in the PCNSL negative (PCNSL-) group (B,E,H) and in the SCNSL group (C,F,I). ONL = outer nuclear layer, INL = inner nuclear layer, GCL = ganglion cell layer; scale bar 50 µm.