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. 2022 Oct 4;23(19):11757. doi: 10.3390/ijms231911757

Figure 2.

Figure 2

Fluorescence microscopy of CD20 (red) and CXCR5 (green) double staining of the eyes in the PDX PCNSL vs. PDX SCNSL group. (A–C) show recordings of the choroid, (D–F) of the retina and (G–I) of the ciliary body (marked with *). (A,D,G) show the choroid, retina, and ciliary body infiltrated with CD20-positive primary CNS lymphoma cells (PCNSL+), which additionally express CXCR5 (triangles). Neither CD20- nor CXCR5-positive cells were found in the PCNSL negative (PCNSL-) group (B,E,H) and in the SCNSL group (C,F,I). ONL = outer nuclear layer, INL = inner nuclear layer, GCL = ganglion cell layer; scale bar 50 µm.