Box Plots of IRS values of CD20, CXCR7, CXCR5, CXCR4, and CD44 of the choroid, the retina, and the ciliary body in the PCNSL vs. SCNSL group. (A) Box plots of IRS values in the choroid of the PCNSL vs. SCNSL group. The IRS was significantly higher for CD20 (marked with asteriks *** p < 0.001), CXCR5 (marked with asterisks *** p < 0.001), CXCR4 (marked with asterisks * p < 0.05) and CD44 (marked with asterisks *** p < 0.001) in the PCNSL compared to the SCNSL group. (B) Box plots of IRS values in the retina of the PCNSL vs. SCNSL group. The IRS was significantly higher for CD20 (marked with asterisks ** p < 0.01) and CXCR4 (marked with asterisks *** p < 0.001) in the PCNSL compared to the SCNSL group. (C) Box plots of IRS values in the ciliary body of the PCNSL vs. SCNSL group. The IRS was significantly higher for CXCR5 (marked with asterisks ** p-value < 0.01) in the PCNSL compared to the SCNSL group. ns = not significant.