Table 2.
Differential expression caused by the low-protein (LP) diet at E20, P0, and P2 in the 10 most up- or downregulated transcripts.
| Gene Symbol | Gene Name | E20 | Gene Symbol | Gene Name | P0 | Gene Symbol | Gene Name | P2 |
|---|---|---|---|---|---|---|---|---|
| Increased | LP vs. Control (Fold Regulation) | Increased | LP vs. Control (Fold Regulation) | Increased | LP vs. Control (Fold Regulation) | |||
| Agtr2 | Angiotensin II receptor, type 2 | 11 | Apoa4 | Apolipoprotein A4 | 142 | Lgals4 | Lectin, galactose binding, soluble 4 | 236 |
| LOC686892 | Muscleblind-like 1 isoform d | 8.7 | Pga5 | Pepsinogen 5 | 112 | Pga5 | Pepsinogen 5 | 215 |
| Cav | Caveolin | 8.6 | Rbp2 | Retinol binding protein 2 | 86 | Agr2 | Anterior gradient 2 | 110 |
| Ppp3r1 | Calcineurin B, type I | 8.5 | Lgals4 | Lectin, galactose binding, soluble 4 | 79 | Retnla | Resistin like alpha | 93 |
| Zfp260 | Zinc finger protein 260 | 7.7 | Tff1 | Trefoil factor 1 | 73 | Fabp1 | Fatty acid binding protein 1 | 92 |
| Sept2 | Septin 2 | 7.6 | Clca3 | Chloride channel calcium activated 3 | 55 | Tff1 | Trefoil factor 1 | 87 |
| Ogn | Osteoglycin | 7.4 | Agr2 | Anterior gradient 2 | 48 | Gkn1 | Gastrokine 1 | 82 |
| Mat2a | Methionine adenosyltransferase II, alpha | 6.3 | Fabp2 | Fatty acid binding protein 2 | 46 | LOC56825 | Prochymosin | 66 |
| Il13ra1 | Interleukin 13 receptor, alpha 1 | 5.9 | Clca6 | Chloride channel calcium activated 6 | 45 | Clca3 | Chloride channel calcium activated 3 | 42 |
| LOC498358 | Solute carrier family 30 (zinc transporte), member 9 | 5.6 | Gkn1 | Gastrokine 1 | 42 | Sult1b1 | Sulfotransferase family 1B | 39 |
| Decreased | LP vs. Control (Fold Regulation) | E20 | Decreased | LP vs. Control (Fold Regulation) | P0 | Decreased | LP vs. Control (Fold Regulation) | P2 |
| Fos | FBJ murine osteosarcoma viral oncogene | −14 | Myo5c | Myosin Vc | −5.1 | Atp8b1 | ATPase, Class I, type 8B, member 1 | −11 |
| LOC680231 | Chromodomain helicase DNA binding protein 9 | −12 | Phlda1 | Chromodomain helicase DNA binding protein 9 | −4.3 | Aff4 | AF4/FMR2 family, member 4 | −9.9 |
| Zfhx1b | Zinc finger homeobox 1b (ZEB2) | −6.8 | Gtl2 | GTL2, imprinted maternally expressed untranslated | −4.2 | Foxo1a | Forkhead box O1A | −9.6 |
| Atxn2 | Ataxin 2 | −6.7 | Smoc1 | SPARC-related modular calcium binding protein 1 | −4.1 | Eif2c2 | Eukaryotic translation initiation factor 2C, 2 | −9.4 |
| RGD1561386 | CBL E3 ubiquitin protein ligase | −6.4 | LOC682488 | Ras-related protein Rab-1B | −4.1 | Tns | Tensin | −9.0 |
| Adipor2 | Adiponectin receptor 2 | −6.1 | Lamc1 | Laminin, gamma 1 | −3.9 | Akap9 | A kinase (PRKA) anchor protein 9 | −8.9 |
| Eif2c2 | Eukaryotic translation initiation factor 2C, 2 | −5.8 | Adhfe1 | Alcohol dehydrogenase, iron containing, 1 | −3.9 | Ash1l | Absent, small, or homeotic)-like | −8.8 |
| Mt1a | Metallothionein 1a | −5.8 | Fgfr1 | Fibroblast growth factor receptor 1 | −3.8 | Rck | DEAD box protein rck/p54 | −7.4 |
| Tbl1x | Transducin (beta)-like 1 X-linked | −5.8 | P34 | P34 protein | −3.7 | Tbl1x | Transducin (beta)-like 1 X-linked | −7.4 |
| Atp8b1 | ATPase, Class I, type 8B, member 1 | −5.4 | Ccnl2 | Cyclin L2 | −3.5 | Ubn1 | Ubinuclein 1 | −6.7 |
Relative transcript abundances at the respective time points. Downregulation is denoted as a negative fold change. Only robustly expressed transcripts (intensity above 100 for at least one time point) were included.