Figure 9.

Acute METH exposure induces anxiety. (A) Anxiety test, light, and dark test (LDT) results include exploration map in the lightbox, Travel distance in the lightbox (m), Light/dark boxes transitions, and time spent in the dark box; (B) Anxiety test, open field test (OFT) results including exploration map in the arena, Travel distance in the arena (m), time spent in corners and center, transition in corners and center, and immobility (grooming) period; (C) Anxiety test, elevated maze test (EMT) results including time spent in open and closed arms, and transition between open and closed arms. Results are expressed as mean ± standard error of the mean (SEM). * p < 0.05, ** p < 0.01, *** 0.001 < p < 0.01, **** p < 0.001.