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. 2022 Sep 20;23(19):11012. doi: 10.3390/ijms231911012

Table 1.

Selected biological functions assigned to different members of the galectin family.

Galectin Individual Functions
Galectin-1
  • Incites apoptosis in initiated T-cells

  • Smothers Th1 and Th17 insusceptible reactions

  • Adds to the immuno-suppressive movement of administrative cells

  • Adds to elective actuation of macrophages

  • Favors tumor development and relocation

  • Advances muscle cell separation

  • Upgrades axonal recovery

  • Advances expansion of neural undeveloped cells

  • Adds to pre-m-RNA joining

  • Controls platelet work

Galectin-2
  • Incites apoptosis in initiated T-cells

  • Ties to lymphotoxin

Galectin-3
  • Contribute to pre-m-RNA splicing

  • Induces apoptosis of T-cell (extracellular) and protects T-cell from apoptosis

  • Potentiates eosinophil migration and promotes neutrophile transmigration and degranulation

  • Favours Th2 responses (extracellular) and Th1 responses (intracellular)

  • Promotes pro-inflammatory cytokine secretion.

  • Favors mast cell degranulation

Galectin-4
  • Takes an interest in the arrangement of lipid pontoons.

  • Instigates the union of IL-6 by CD4+T cells.

  • Profoundly communicated amid growth movement.

Galectin-7
  • Partakes in keratinocytes separation. Khunmod

  • Intercedes the master apoptotic impacts of p63 in keratinocytes.

  • Over-communicated in metastatic mouse lymphoma cells.

Galectin-8
  • Tweaks collaboration of integrins with extracellular lattice

  • Upgrades glue properties of neutrophiles

  • Smothers movement of growth cells

  • Tweaks endocytosis of cell-surface receptors

Galectin-9
  • Tweaks collaboration of integrins with extracellular lattice

  • Upgrades adhesive properties of neutrophiles

  • Smothers movement of growth cells

  • Tweaks endocytosis of cell-surface receptors

  • Chemoattractant of eosinophiles

Galectin-10
  • Has an important role in T-regulatory cells function

Galectin-12
  • Prompts apoptosis of adipocytes

  • Partakes in the control of cell cycle movement

  • Partakes in adipocyte separation