Table 1.
The literature data on parameters of the heterogeneous ligand model (1), describing the SPR data on kinetics of interaction between Ca2+-loaded S100P and four-helical cytokines at 25 °C (cytokine immobilization on the sensor chip surface by amine coupling).
| Cytokine | Kd1, M | Kd2, M | Reference |
|---|---|---|---|
| Short-chain cytokines | |||
| EPO | (5.4 ± 1.2) × 10−7 | (1.8 ± 0.5) × 10−6 | [22] |
| Long-chain cytokines | |||
| IL-11 | (3.2 ± 0.3) × 10−8 | (2.88 ± 0.01) × 10−7 | [28] |
| Cardiotrophin-like cytokine factor 1 | (8.1 ± 2.6) × 10−8 | (1.4 ± 0.8) × 10−7 | [21] |
| Ciliary neurotrophic factor | (1.0 ± 0.6) × 10−7 | (1.1 ± 0.8) × 10−7 | [21] |
| Cardiotrophin-1 | (1.9 ± 0.5) × 10−8 | (9.8 ± 2.7) × 10−7 | [21] |
| Oncostatin-M | (7.0 ± 4.2) × 10−7 | (2.0 ± 0.9) × 10−6 | [21] |
| Interferons/IL-10 | |||
| IFN-β | (5.34 ± 0.10) × 10−8 | (6.1 ± 2.3) × 10−7 | [10] |