Table 4.

Significant compounds in (colorectal cancer and advanced adenoma vs. control) and (pre-surgery and post-surgery) comparisons, including the relevant identifiers. Asterisk indicates that the compound is found relevant in the pathways and enrichment analysis.

Compound Name	MW	Chemical Formula	PubChem ID	HMDB ID	KEGG ID	Reference
Creatinine	113.12	C4H7N3O	588	HMDB0000562	C00791	[22,23,25]
4-Hydroxybenzoic acid	138.12	C7H6O3	135	HMDB0000500	C00156	[25] †
Acetone	58.08	C3H6O	180	HMDB0001659	C00207	[24,25]
Carnitine	161.20	C7H15NO3	288	HMDB0000062	C00318	[25,27]
D-Glucose	180.16	C6H12O6	5793	HMDB0000122	C00031	[25] †
Hippuric acid	179.17	C9H9NO3	464	HMDB0000714	C01586	[22,23]
L-Lysine	146.19	C6H14N2O2	5962	HMDB0000182	C00047	[25] †
L-Threonine	119.12	C4H9NO3	6288	HMDB0000167	C00188	[22,27]
* Pyruvic acid	88.06	C3H3O3	1060	HMDB0000243	C00022	[25,27]
* Acetic Acid	60.05	C2H4O2	176	HMDB0000042	C00033	[25] †
Phenylacetylglutamine	264.28	C13H16N2O4	92,258	HMDB0006344	C05598	[25] †
Urea	60.06	CH4N2O	1176	HMDB0000294	C00086	[22,27]

^† Reference [25] has different analyses of a cohort with different time points.