Table 4.
Minimum inhibitory and fungicidal concentration values (MIC/MFC) in µg/mL for compounds 1–4 against Candida yeasts isolated from patients with Candidemia.
| Compound | MIC/MFC (µg/mL) | |||||
|---|---|---|---|---|---|---|
| Candida Yeast Type | ||||||
| C. albicans | C. krusei | C. glabrata | C. tropicalis | C. parapsilopsis | C. lusitaneae | |
| 1 | 3.75/- | 7.5/- | 15.0/- | 15.0/- | 7.5/- | 7.5/- |
| 2 | 15.0/60 | 3.75/50 | 3.75/60 | 7.5/50 | 15.0/60 | 1.9/50 |
| 3 | 50.0/50 | 25.0/25.0 | 25.0/25 | 50.0/60 | 50.0/60 | 6.25/6.25 |
| 4 | -/- | -/- | -/- | -/- | 50.0/- | -/- |
| Control | 0.8 | 12.5 | 3.13 | 0.8 | 0.8 | 0.8 |
Control: Fluconazole. (-) Not active at concentrations > 60 µg/mL.