Effects of selenium, exosomes, and selenium-treated exosomes on the inflammatory response. (A) Relative gene expression related to pro-inflammation (TNF-α, IL-6, and IL-8) and anti-inflammation (TGF-β1 and IL-10) was evaluated by real-time PCR after LPS treatment. Relative gene expression levels of CD163, CD206, and Arg1 were detected. (B) A multiplex assay was conducted to detect the concentrations of IL-6 and IL-10 in the conditioned media. Data are expressed as the mean ± SD of three independent experiments. * Significant difference from control, p < 0.05. ** Significant difference from control, p < 0.01.