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Effect of trimetazidine (TMZ) on the brain levels of (A) valproate (VPA), (B) carbamazepine (CBZ), (C) phenobarbital (PB), and (D) phenytoin (PHT). Results are presented as the ±SD (in µg/mL) of at least eight determinations. Statistical analysis was performed using an unpaired Student’s test. TMZ—trimetazidine, VPA—valproate, CBZ—carbamazepine, PB—phenobarbital, and PHT—phenytoin.
