Table 1.
MicroRNAs as biomarkers for diagnosis and prognosis of NSCLC.
| miRNA | Sample | Expression | AUC | Biomarker | Reference |
|---|---|---|---|---|---|
| miR-708-5p | Tissue | ↑ | 0.925 | Diagnosis | [40] |
| miR-1247-5p | Serum | ↑ | 0.812 | Diagnosis | [41] |
| miR-301b-3p | Serum | ↑ | 0.788 | Diagnosis | [41] |
| miR-105-5p | Serum | ↑ | 0.793 | Diagnosis | [41] |
| miR-492 | Plasma | ↑ | 3-miR:0.828 | Diagnosis | [49] |
| miR-590-3p | Plasma | ↑ | 3-miR:0.828 | Diagnosis | [49] |
| miR-4507 | EBC | ↑ | 3-miR:0.837 | Diagnosis | [50] |
| miR-451a | EBC | ↑ | 3-miR:0.837 | Diagnosis | [50] |
| miR-483-5p | exosomes | ↑ | / | Diagnosis | [39] |
| miR-342-5p | exosomes | ↑ | / | Diagnosis | [39] |
| miR-520c-3p | exosomes | ↑ | 2-miR:0.857 | Diagnosis | [51] |
| miR-1274b | exosomes | ↑ | 2-miR:0.857 | Diagnosis | [51] |
| miR-96 | exosomes | ↑ | 0.9735 | Diagnosis/Prognosis | [52] |
| miR-1276 | Tissue | ↑ | / | Prognosis | [46] |
| miR-767-3p | Tissue | ↑ | / | Prognosis | [46] |
| miR-767-5p | Tissue | ↑ | / | Prognosis | [46] |
| miR-10b | Tissue | ↑ | / | Prognosis | [53] |
| miR-135b | Tissue | ↑ | / | Prognosis | [54] |
| miR-142-3p | Tissue | ↑ | / | Prognosis | [55] |
| miR-196a | Tissue | ↑ | / | Prognosis | [56] |
| miR-202 | Plasma | ↑ | / | Prognosis | [57] |
| miR-17 | Tissue | ↓ | 0.692 | Diagnosis | [38] |
| miR-125b-5p | Tissue | ↓ | 0.768 | Diagnosis/Prognosis | [44] |
| miR-631 | Plasma | ↓ | 3-miR:0.828 | Diagnosis | [49] |
| miR-6777-5p | EBC | ↓ | 3-miR:0.837 | Diagnosis | [50] |
| miR-23a | exosomes | ↓ | 0.744 | Diagnosis | [58] |
| miR-let7i | exosomes | ↓ | 0.733 | Diagnosis | [58] |
| miR-203 | Tissue | ↓ | / | Prognosis | [53] |
| miR-320a | Serum | ↓ | / | Prognosis | [47] |
EBC: exhaled breath condensate, 3-miR: AUC values of three miRNA combinations appearing in the same paper, 2-miR: AUC values of two miRNA combinations appearing in the same paper, ↑: Up-regulated expression, ↓: Down-regulation expression.